A Las Vegas team of forensic investigators are trained to solve criminal cases by scouring the crime scene, collecting irrefutable evidence and finding the missing pieces that solve the mystery.
A wild night in Las Vegas has the CSIs simultaneously investigating four fatalities. Greg Sanders' first day in the field has him assisting Grissom's investigation of a fatal nightclub shooting. Meanwhile, Catherine probes into the death of a stripper found dead in a hotel room, while Sara and Nick look into the strange case of an "alien" body found near Area 51.